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Areas of work

Biostatistics

Statistical work on a defined question, where the requirement is a senior statistician rather than a complete study.

Methods used routinely include survival analysis with competing risks and time-varying exposure, mixed-effects models for repeated measures, propensity score and G-methods for causal questions, multiple imputation with sensitivity to the missingness mechanism, sample size and precision calculation, and prediction model development and validation. Analysis is conducted in R and organised so that it can be re-run from source data by someone else. Machine learning and large language model tools are used where they improve the analysis or its documentation, under the same pre-specification and verification requirements as any other method. Shorter consultancy on a single analysis, for researchers and clinicians in Denmark, is described under statistical consultant in Denmark (dansk).

Real-world evidence studies

Observational studies designed around a stated question rather than around the data that happen to be available.

The Nordic registers offer national coverage, linkage across health, prescription and socioeconomic records, and decades of near-complete follow-up. They also carry constraints that shape a design: limited clinical detail, coding practice that changes over calendar time, and access through secure environments. Method follows the question. Target trial emulation is used where the question is causal, propensity or overlap weighting where confounders are measured, external comparator construction where a single-arm trial has no control group, and descriptive epidemiology where that is what the data can support.

Teaching

Courses built around the participants' own data, setting and tooling.

Teaching has run alongside the research throughout and remains a substantial part of the work. Courses are delivered in house for a single organisation or as open sessions for mixed audiences of clinical researchers, statisticians and analysts. The course catalogue lists the current subjects, prerequisites and formats.

Terms of engagement

FormSuited to
Advisory reviewA defined question requiring a senior second opinion, typically two to five days
Fixed-fee deliverableA protocol, analysis plan, analysis or complete study
RetainerContinuing statistical support across several projects
Course deliveryBuilding analytical capability within a team
Named subcontractSpecialist capacity under a client's own contract

Work is normally quoted as a fixed fee against a defined scope. Rates on request.

Enquiries

Describe the question, the data available and the timescale, and you will receive an assessment of feasibility and of what the work would involve.

Discuss your analysis